FTO Generic, check both Orange Book and FDA information at once

 

 What is the exact meaning of 'generic medicine', which was previously referred to as 'copy drugs'?

It refers to a medicine that is made using the disclosed technology of an original medicine whose patent has expired, and has the same main ingredient, content, formulation, efficacy, and dosage as the original medicine. It is a product that has been recognized by the pharmaceutical management agency of each country, such as the Ministry of Food and Drug Safety, as a product equivalent to the original medicine through a pharmaceutical equivalence test.

 A new medicine that a pharmaceutical company first makes is called an original. This medicine is protected by a patent. Generally, a patent is protected for 20 years from the date of application, but considering the period of product development, the actual effective patent period is about 15-18 years. Unlike other products whose sales volume drops sharply as the patent expiration date approaches, pharmaceutical sales tend to increase rapidly, so the patent protection period is often extended for several years. For this reason, the United States has been implementing the Patent Term Extension (PTE) system since 1984.

 Patent term extension is a system that extends the term of a patent for a certain period of time in cases where the patent cannot be actually enforced due to a long period of time required to obtain regulatory approval (Regulatory Review Period; RRP) during the patent term. After this system was introduced in the United States, other countries have introduced similar systems one after another. Korea also introduced the substance patent system in 1987, and the patent term extension system has been implemented since 1999. Multinational pharmaceutical companies devise protection strategies to effectively utilize the patent term extension system, and generic pharmaceutical companies devise various methods to avoid their patent extension strategies.

 With blockbuster diabetes treatment drugs set to expire one after another in the next three years, generic pharmaceutical companies are seeking various patent strategies to quickly enter the market and take the lead.

 The FDA is publishing the Orange Book to provide information on the evaluation of therapeutic equivalence of various prescription drugs to pharmacists in the United States. The Orange Book contains patent information on approved new drugs, and is used as important data for resolving pharmaceutical patent disputes. WIPS Global provides an FTO Generic search service by implementing a convergence service that links the Orange Book and US patents. Let’s take a look.

wipsglobal.com> FTO Generic

This is the Orange Book search field. You can search from three perspectives: product information, exclusive information, and related patent information (US registered patents).

wipsglobal.com> FTO Generic

 This is the search results screen. Based on the FDA application unit field, the corresponding product field is grouped (product number, type, pharmaceutical product name, patent number, dosage form; administration route, content, therapeutic equivalence code, reference drug) and displayed as a list.

wipsglobal.com> FTO Generic

 Click on the FDA application number to check the detailed information of the corresponding application information. This is a page that provides all the information held by the Orange Book. You can see product information, exclusive information, and related patent information (US registered patents) of the FDA application.

wipsglobal.com> FTO Generic

 Click on the patent number of the related patent (US registered patents) to go to the View Details and check detailed information such as bibliography, claims, description, trial/litigation, and chemical compounds.

wipsglobal.com> FTO Generic

 The related patent list is connected to ‘My Folder’ and ‘Easy Viewer’, so you can save it in My Folder or quickly review multiple patents.

wipsglobal.com> FTO Generic

 We provide a list of pharmaceutical patents that can be freely implemented. You can review the list of expired pharmaceuticals by selecting the year of expiration and the year of upcoming expiration.

 So far, we have looked at the FTO Generic search features provided by WIPS Global. 

Please make use of FTO Generic to view detailed information on new drugs and related patents from the Orange Book.

 

[International IP Briefing] JP, US

JP 

Patent Result Co.,Ltd in Japan announces ‘Pharmaceutical Industry Patent Asset Size Ranking 2024’

On October 30, 2024, Japanese Patent Result announced the ‘Pharmaceutical Industry Patent Asset Size Ranking 2024 (特許資産規模ランキング2024)’, which comprehensively evaluated the quality and quantity of patent assets held by each pharmaceutical company based on the Patent Result company’s own classification.

The Patent Result company assumed the patents held by companies (patent registrations approved by the Japan Patent Office, and not expired or abandoned) as ‘patent assets’ and calculated the patent score as an index for comprehensively judging the size of patent assets.

∙ The TOP 3 were ranked by evaluating patent scores for patents registered for one year from April 1, 2023 to the end of March 2024. F. HOFFMANN LA ROCHE ranked 1st, Merck ranked 2nd, and Pfizer ranked 3rd.

∙ Among La Roche’s most notable patents are ‘Novel heterocyclic compounds for the treatment of autoimmune diseases’ and ‘Thermal treatment device for in vitro diagnostic test samples’, and both technologies have been applied for in Japan, as well as with the EPO, the US, China, and other countries.

∙ Merck, ranked in 2nd, include ‘physical object tracking system for preventing product counterfeiting using automatic identification and authentication technology’ and ‘purification process for biopharmaceuticals and plasma derivatives using cellulose-containing filter materials’.

∙ Pfizer’s notable patents, ranked third, include technologies related to ‘antibodies that specifically bind to proteins (CD3) and their use to regulate immune responses and inhibit tumor growth’ and ‘cancer treatment inhibitors with desirable properties such as high crystallinity, purity, and stability.’

 

< source of the post >

https://www.kiip.re.kr/board/trend/view.do?bd_gb=trend&bd_cd=1&bd_item=0&po_item_gb=JP&po_no=23215

 

US

The U.S. Artificial Intelligence Safety Institute (USAISI) announces the launch of the Testing Risks of AI for National Security (TRAINS)

On November 20, 2024, the U.S. Artificial Intelligence Safety Institute (USAISI) announced the formation of the Testing Risks of AI for National Security (TRAINS) Task Force (hereinafter referred to as the TRAINS Task Force).

USAISI, an agency within the National Institute of Standards and Technology (NIST) of the U.S. Department of Commerce (DOC), launched the TRAINS Task Force for National Security by bringing together partners from across the U.S. government to identify, measure, and manage emerging national security and public safety implications of rapidly evolving AI technology.

The TRAINS Task Force is chaired by USAISI and is comprised of four federal agencies (①-④). Each agency will provide expertise and resources to the TRAINS Task Force and collaborate on the development of new AI evaluation methods and benchmarks, as well as conduct joint training for national security risk assessment.

①The Department of Defense (DOD), including the Chief Digital and Artificial Intelligence Office (CDAO) and the National Security Agency

②The Department of Energy (DOE) and ten of its National Laboratories

③The Department of Homeland Security (DHS), including the Cybersecurity and Infrastructure Security Agency (CISA)

④The National Institutes of Health (NIH) at the Department of Health and Human Services (HHS)

Purpose and Role

∙ The TRAINS Taskforce, comprised of experts from U.S. federal agencies, aims to solve national security issues and strengthen America’s AI leadership.

∙ It will enable collaborative research and testing of advanced AI models in critical national security and public safety areas, including radiological and nuclear security, chemical and biological security, cybersecurity, critical infrastructure, and military capabilities.

∙ It will also maintain America’s leadership in AI development and prevent countries from misusing American innovation to undermine our national security.

- (Related)

Enabling safe, secure, and trustworthy AI innovation is not just an economic priority – it's a public safety and national security imperative,” said U.S. Secretary of Commerce Gina Raimondo. “Every corner of the country is impacted by the rapid progress in AI, which is why establishing the TRAINS Taskforce is such an important step to unite our federal resources and ensure we’re pulling every lever to address the challenges of this generation-defining technology. The U.S. AI Safety Institute will continue to lead by centralizing the top-notch national security and AI expertise that exists across government in order to harness the benefits of AI for the betterment of the American people and American business.”

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< source of the post >

https://www.kiip.re.kr/board/trend/view.do?bd_gb=trend&bd_cd=1&bd_item=0&po_item_gb=US&po_no=23277

Cooking tools for making food and its patents

 

  Recently, a cooking competition program called 'Culinary Class Wars' on Netflix has become very popular in Korea. When you watch chefs selected from all over the country compete and collaborate to create artistic dishes, you can't help but get absorbed in it without realizing how much time has passed. This time, let's learn about the various cooking tools and patents that make food.

 The world of various cooking tools

  When you watch cooking programs, you can see not only cooking, but also various and novel cooking methods that you can't usually see. From molecular cooking machines that make dishes with molecules to sous vide machines that slowly heat ingredients in a vacuum, there are so many different cooking tools. Let's find out what technology was used to create these cooking tools.

clipartkorea.co.kr

Sous vide machine that heats and warms meat with water instead of fire

 'Sous vide' refers to a cooking method that slowly heats food such as meat in a sealed bag with water at a precisely calculated temperature. The core principle of this sous vide cooking method is to accurately determine the temperature at which the protein denaturation begins and to adjust the temperature and time to denature it exactly as the chef wants.

Michelin Guide
(source: https://guide.michelin.com/kr/ko/article/features/%EC%88%98%EB%B9%84%EB%93%9Csous-vide%EB%9E%80 )

  In particular, meat has the characteristic of becoming softer as it cooks, but hardens again when overcooked, so it is said that the meat is most delicious and nutritious when cooked at a temperature of 50-65 degrees for a long time to minimize denaturation. In the end, since precise temperature control is the most important for sous vide cooking, the key is which cooking tool you use to do sous vide. I was able to find out that there are various sous vide machines.

First, let's take a look at the most basic sous vide machine.

  This device is made to evenly transfer heat to meat products, and is designed to circulate fluids harmoniously by discharging microbubbles inside the tube where meat products are put. The feature of this device is that the impeller is installed inside the tube, allowing smooth air injection to maintain heat distribution and optimal temperature control.

wipsglobal.com
KR10-2022-0116132, 'Full flat reclining device for camping vehicle'

  Meanwhile, a sous vide device that does not require vacuum packaging, which is considered essential for sous vide cooking, has also been developed. In fact, sous vide cooking increases cooking time and is inconvenient due to the process of putting preprocessed food in a vacuum packaging bag and performing a vacuum. Therefore, this device was designed to reduce this vacuum packaging process and implement the same vacuum packaging effect. The main principle is the use of a unique fixing unit that enables sealing and vacuum effects.

wipsglobal.com
KR10-2022-0166548, 'Sous vide device that does not require vacuum packaging'

  It is said that the vacuum effect is implemented by fixing the fixing unit to the stand and supporting the storage medium by moving the fixing stand. In addition, it is said that it is equipped with additional devices such as sensors, timers, and abnormal condition notification devices so that the user can set the desired temperature and time, making it easy to perform other tasks while the material is being sous vide.

Noodle maker and pasta maker

 This is the most basic ‘noodle maker’ for pasta. This noodle maker is a noodle maker that can directly make various types of noodles such as pasta, noodles, and udon noodles.

wipsglobal.com
KR20-2017-0005323, 'Apparatus for making noodles'

  However, this noodle maker is designed to maintain a constant noodle thickness by making up for the disadvantage of the uneven thickness of the pulled noodles. The operation method is simple. This is a method where you put kneaded flour between the rollers of a noodle maker and turn the lever so that the rollers rotate and thin noodles are pulled out.

  There is also a portable, fully automatic pasta production device that allows you to make your own pasta dishes. Even simple-looking pasta dishes actually require a lot of processes, including direct measurement and addition of dough for the noodles, as well as final completion.

wipsglobal.com
KR10-2024-7005208, 'A pasta product production device and method of use thereof'

  With this device, you can make delicious pasta in no time with just one click order. The pasta production device is equipped with a powder distribution function to evenly distribute the flour, a water distribution function, and additive injection function. When the motor is turned on, these functions perform their roles well and you can perfectly cook the pasta you want.

Nitrogen-created melted foam and cream ‘Espuma’

  Espuma is a technique that creates foam using a whipped cream dispenser. Nitrogen gas can be injected into various liquid or puree materials to create a light and soft foam.

(source: https://rchemyagent.com/shop/item.php?it_id=1477648360 )

  What technologies and devices are there for Espuma? First, let's look at the nitrous oxide supply device. It is a device that can safely supply nitrous oxide used when making whipped cream in restaurants and cafes. This device has a pressure control unit that can simply control the flow of nitrous oxide, a safety unit, and 1st and 2nd valves, so it is said that simple pressure control and safe injection into a whipping machine are possible.

wipsglobal.com
KR10-2020-0111560, 'A nitrous oxide dispension apparatus'

  There is also a whipping cream maker. This whipping cream maker is that can form high-quality whipped cream by mixing only cream and whipping gas and minimizing the amount of air. This machine is equipped with a special part called a ‘elasticity bag’ (like a flexible pocket), and have an excellent effect of minimizing impurities such as air even when the bag is filled with cream and nitrogen gas is injected.

wipsglobal.com
KR10-2013-0003993, 'Whipped cream making device'

The world of cooking tools, even more exciting in the future

  This time, we learned about the technology of cooking tools. Cooking has now become a new field where science and technology meet. Now that we can easily access Michelin-starred food, we look forward to seeing what kind of food and cooking tools will catch our eyes and mouths in the future.

clipartkorea.co.kr